Cannabis has long been used to aid sleep. A frequent lack of sleep can have a significant impact on mental and physical wellbeing. But using. Is cannabis an answer to entering the land of sleep? From strains to timing, here's what you need to know about cannabis as a nightcap. I thought I'd take some time to go over some information that may be helpful in understanding how cannabis can affect sleep and sleep-related.
cannabis Can for sleeping? you use
OSA has been documented in studies of chronic pain patients with disorders such as rheumatoid arthritis and fibromyalgia. Studies of patients with symptoms of fibromyalgia have led some investigators to propose that certain individuals may instead have a sleep apnea syndrome and the medications prescribed for fibromyalgia would actually worsen the sleep apnea symptoms [ 27 ].
OSA is more prevalent in chronic pain patients who use opioid-based drugs for pain management compared to the general population [ 28 ]. Sleep apnea is also frequently linked to headaches [ 27 ]. Cannabinoids and Sleep Clinical cannabis research is predominantly focused on symptom management using compounds derived from cannabis called cannabinoids, and it has been suggested that one of the additional benefits of cannabinoid use is increasing sleep quality.
Indeed one of the main reasons that patients report using herbal cannabis is to improve sleep quality [ 29 ]. Given our improved understanding of the endocannabinoid system ECS , It is worth exploring the underlying rationale for this effect.
Anatomical data suggests that the CB1 receptor may be involved in the modulation of sleep [ 7 ]. Research on cannabis and THC extract from the s and s showed that cannabinoids have an effect on sleep by increasing SWS and decreasing REM sleep , but these studies were poorly controlled.
The earliest reported studies of the primary psychoactive cannabinoid deltatetrahydrocannabinol THC on sleep explored the hypnotic effects of different dose levels of THC [ 30 ]; the effect of the isomer deltaTHC on EEG activity and sleep was explored in cats [ 31 ] and rats [ 32 ].
In a single dose human study examining cannabinoid effects on sleep, administration of CBD alone increased wakefulness, while THC was found to have no adverse effect on sleep and in some individuals increased the amount of SWS. The physiological role of endocannabinoids on sleep has been explored. The effect of AEA effect was enhanced when injected into the pedunculopontine tegmental nucleus.
It was hypothesized that AEA, acting through CB1, induces an increase in the activity of the cholinergic neurons of the brainstem and basal forebrain that are involved in inducing sleep. Clinical Evidence It is important to recognize that the effects of cannabis on sleep have been examined in recreational users as well as patients. Among heavy cannabis users, shorter REM latency and a longer sleep onset have been observed compared to controls [ 33 ].
Cessation of long-term heavy use of cannabis reduces sleep quality by decreasing total sleep length as well as the amount of SWS [ 34 ]. Poor sleep quality was one of the reasons that abstinent heavy cannabis users relapse [ 35 ]. Among patients with chronic pain, early experience with the synthetic cannabinoid nabilone found that one of the main reasons nabilone was continuously used was due to improvement in sleep quality .
Other observational studies have found that smoked cannabis is used by patients with chronic non-cancer pain to help decrease their pain and improve sleep [ 37 ]. Cannabis use in patients with post-traumatic stress disorder has also been reported to increase sleep quality [ 38 ]. Clinical trials with synthetic cannabinoids have shown some promise for dealing with sleep and pain.
A study by Notcutt et al. CBD reduced pain scores in patients but had little to no effect on the duration of sleep, while the perceived quality of sleep increased dramatically. Nabiximols, an oromucosal drug containing a 1: CBD drug has been tested for its effectiveness on pain and sleep interactions in several pain conditions including multiple sclerosis MS [ 2 ]. Nabiximols has been shown to reduce insomnia and daytime fatigue and to improve sleep quality in both MS and neuropathic pain patients.
In the patients in whom it was beneficial, no evidence of tolerance or cognitive problems was noted [ 2 ]. They found that nabiximols was effective in reducing pain and pain-related sleep disturbances. Nabiximols was also tried on patients with rheumatoid arthritis and was found significantly reduce pain on movement, pain and rest and the quality of sleep [ 41 ]. A study done by Ware et al. FM-related insomnia is usually treated with low-dose tricyclic antidepressants such as amitriptyline.
However, nabilone was found to be superior to amitriptyline in improving the sleep quality of FM patients while the effects on pain, mood and quality of life were similar. Drowsiness and dizziness were common adverse events but these were similar to the side effects of amitriptyline.
Dronabinol, a synthetic version of THC, has been found to be useful for nighttime agitation related to severe dementia. Nighttime motor activity was found to decrease in dementia sufferers after the first dose of dronabinol, and while the mechanism of action is not clear, it may be due to sleep induction.
Dronabinol was found to have dose dependent side effects and other studies showed effects on the cognition and function of patients but this was not examined in this study [ 43 ]. Dronabinol has also demonstrated effectiveness in treating central pain due to MS [ 44 , 45 ]. Intriguingly, THC has been found to stabilize respiratory patterns during all sleep stages and reducing sleep apnea in a dose dependent fashion [ 46 ]. A systematic review of cannabinoids and sleep completed in , which addresses many of the articles presented above, points to the fact that many of the studies have bias and were not properly controlled.
Despite the poor studies the authors of the review state that cannabinoids may play a role in sleep most specifically when pain is involved but the current evidence was not sufficient enough to say for certain [ 1 ]. What Needs to be Studied? Sleep is a complex and poorly understood phenomenon integral to quality of life.
Cannabinoids appear to have a potential role in improving perceived sleep quality, but overall there is very little data on the effects of cannabinoids on sleep architecture. It will be important to demonstrate the long term effects of cannabis and cannabinoid-based medicines, like nabilone and nabiximols, as well as medical cannabis on sleep. They should be validated by further randomized clinical trials and long term surveillance studies [ 37 ].
Some insomnia sufferers use high-CBD strains to fall asleep, says Rebecca Haines-Saah, an assistant professor in the department of community health science at the University of Calgary, who specializes in drugs and substance use.
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Legalization of Cannabis Legalization of Marijuana Life. Does marijuana affect your sex drive? Also known as sleeplessness, insomnia is a sleep disorder where one has trouble sleeping, typically followed by daytime sleepiness, low energy levels, irritability or a depressed mood. It can be short term, lasting for days or weeks, or long term, lasting more than a month. Ce service ne requiert aucun formulaire de demande.
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Can pot help you sleep better? The truth about how cannabis affects your health
Many people are using cannabis as a sleeping medication but does it really work . while alcohol initially can make you drowsy and even increases deep sleep. However, the effects can vary quite substantially between THC- and Are you trying to decide between using CBD or THC as medication for. This comparison article brought to you by Canabo Medical Inc. details While this type of conventional medication can be an effective cannabis and sleeping pills is the fact that the former is safe to use over the long term.